Blar i forfatter "Nilsen, Dennis W.T."

Viser treff 1-4 av 4

    • The Effect of Protease-Activated Receptor-1 (PAR-1) Inhibition on Endothelial-Related Biomarkers in Patients with Coronary Artery Disease 

      Nilsen, Dennis W.T.; Røysland, Michelle; Ueland, Thor; Aukrust, Pål; Michelsen, Annika Elisabet; Staines, Harry; Barvik, Ståle; Kontny, Frederic; Nordrehaug, Jan Erik; Bonarjee, Vernon V S (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-20)
      Abstract Background: Vorapaxar has been shown to reduce cardiovascular mortality in postmyocardial infarction (MI) patients. Pharmacodynamic biomarker research related to protease-activated receptor-1 (PAR-1) inhibition with vorapaxar in humans has short follow-up (FU) duration and is mainly focused on platelets rather than endothelial cells. Aim: This article assesses systemic changes in ...

    • Incidence and risk factors for major bleeding among patients undergoing percutaneous coronary intervention: Findings from the Norwegian Coronary Stent Trial (NORSTENT) 

      Samuelsen, Per-Jostein; Eggen, Anne Elise; Steigen, Terje; Wilsgaard, Tom; Kristensen, Andreas; Skogsholm, Anne; Holme, Elizabeth; van den Heuvel, Christian; Nordrehaug, Jan Erik; Bendz, Bjørn; Nilsen, Dennis W.T.; Bønaa, Kaare Harald (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-04)
      Introduction - Bleeding is a concern after percutaneous coronary intervention (PCI) and subsequent dual antiplatelet therapy (DAPT). We herein report the incidence and risk factors for major bleeding in the Norwegian Coronary Stent Trial (NORSTENT). <p> <p>Materials and methods - NORSTENT was a randomized, double blind, pragmatic trial among patients with acute coronary syndrome or stable coronary ...

    • Plasma concentrations and dietary intakes of choline and betaine in association with atrial fibrillation risk: Results from 3 prospective cohorts with different health profiles 

      Zuo, Hui; Svingen, Gard Frodahl Tveitevåg; Tell, Grethe S.; Ueland, Per Magne; Vollset, Stein Emil; Pedersen, Eva Ringdal; Ulvik, Arve; Meyer, Klaus; Nordrehaug, Jan Erik; Nilsen, Dennis W.T.; Bønaa, Kaare; Nygård, Ottar (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-12)
      <p><i>Background - </i>Although choline metabolism has been associated with atherosclerotic heart disease, less research attention has been paid to the associations of choline and its oxidative metabolite betaine with cardiac arrhythmias. <p><i>Methods and Results - </i>We evaluated associations of plasma concentrations and dietary intakes of choline and betaine with long-term atrial fibrillation ...

    • Vitamin D Uptake in Patients Treated with a High-Dosed Purified Omega-3 Compound in a Randomized Clinical Trial Following an Acute Myocardial Infarction. 

      Næsgaard, Patrycja; Grundt, Heidi; Nordøy, Arne; Staines, Harry; Nilsen, Dennis W.T. (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-07-24)
      Background: <br> Fish is the natural dietary source of vitamin D. Reports on the influence of purified omega-3 fatty acids on its uptake are scarce. <br> Objectives: <br> We investigated the impact of a purified high-dose omega-3 compound compared to corn oil on 25-hydroxyvitamin D [25(OH)D] levels following an acute myocardial infarction. <br> Methods: <br> 228 patients were randomized 1:1 to receive ...